Director, Strategic Alliances & External Engagement – Medical Affairs

“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky” Mineralys is a fully remote company. Role Overview The Director of Strategic Alliances & External Engagement is a senior leader within Medical Affairs responsible for developing and executing a cross-functional coordinated engagement strategy that strengthens Mineralys’ scientific leadership in cardio-renal-metabolic disorders. This role drives collaboration across academic institutions, professional societies, patient advocacy organizations, and other key external stakeholders to support the full product lifecycle of lorundrostat, Mineralys’ first-in-class aldosterone synthase inhibitor. By aligning external partnerships with the company’s medical and corporate objectives, this leader ensures that actionable insights, scientific data, and real-world evidence shape how Mineralys advances its mission to improve outcomes for patients with uncontrolled and resistant hypertension. Core responsibilities Forge and manage strategic partnerships. Identify, evaluate, and cultivate high-impact relationships with leading academic investigators, clinical networks, professional societies, and patient advocacy groups within the hypertension and broader CRM community. Build collaborative frameworks that expand scientific exchange, facilitate data generation, and amplify Mineralys’ visibility in the field. Lead the external engagement strategy and cultivate scientific thought leadership Design and implement an integrated engagement roadmap aligned with Medical Affairs pillars, Scientific Communication Platform, and corporate objectives. Partner closely with field medical, scientific communications, HEOR, and clinical development teams to ensure coordinated and compliant interactions. Lead external collaborations with Key Opinion Leaders (KOLs), digital opinion leaders (DOLs), and academic consortia to deepen understanding of aldosterone-driven disease mechanisms and treatment paradigms. Integrate scientific and clinical insights into medical strategies, field guidance, and future development planning. Clinical practice guideline oversight Serve as the Medical Affairs lead for guideline and compendia inclusion strategy, aligning internal evidence generation, publication planning, and external KOL engagement to meet evidence thresholds for consideration. Build and sustain strategic alliances with key guideline committees, scientific societies, and evidence-based medicine organizations to advocate for inclusion of lorundrostat-related data. Plan and execute advisory board meetings Design, plan, and execute compliant scientific advisory board meetings (virtual and in-person) to obtain actionable insights that inform Medical Affairs strategy, evidence generation, and external engagement priorities. Identify, recruit, and collaborate with key external experts and thought leaders across hypertension, nephrology, and cardiometabolic specialties to ensure diverse, high-quality scientific input. Develop clear strategic objectives, discussion guides, and post-meeting analysis to translate insights into tangible actions supporting launch readiness, guideline inclusion, and value communication. Partner cross-functionally with Compliance, Legal, and Commercial stakeholders to ensure all activities align with corporate governance and OIG standards for external scientific interactions. Oversee engagement strategy with professional organizations Develop and lead the strategic engagement plan with key professional societies and scientific organizations to strengthen Mineralys’ external scientific presence and credibility within the cardio-renal-metabolic community. Oversee planning and execution of scientific sponsorships and society collaborations, ensuring alignment with Medical Affairs objectives, evidence dissemination priorities, and compliance standards. Partner cross-functionally with synchronizing congress strategy, data releases, and post-meeting insight capture. Patient Advocacy initiatives Establish and maintain strategic partnerships with patient advocacy organizations to align on shared goals of disease awareness, education, and equitable access to emerging therapies. Collaborate with patient advocacy organizations to ensure the patient voice informs clinical development, access strategies, and educational initiatives. Medical Grants management Oversee the Medical Affairs grants, sponsorships, and external funding process, ensuring fair, transparent, and compliant review and execution of educational and scientific support requests. Drive cross functional alignment Partner with Clinical Development, R&D, Commercial, Regulatory, and Legal to ensure consistent, compliant, and science-based communication. Serve as an internal ambassador for external engagement excellence, ensuring collaboration is strategic and measured by clear KPIs. Ensure compliance and excellence Establish and uphold the highest ethical standards in external engagement, consistent with corporate compliance policies, PhRMA guidelines, and global regulations. Develop and refine SOPs and best practices for compliant collaboration and sponsorship activities. Qualifications & Experience Advanced scientific or clinical degree (PharmD, PhD, MD, or equivalent) required. 8+ years of experience in Medical Affairs or related functions within the biopharmaceutical industry, including experience leading external collaborations or alliance management. Therapeutic area expertise in cardiovascular, renal, endocrine, or metabolic diseases preferred. Strategic and analytical mindset with a proven ability to translate external insights into actionable medical strategies. Strong leadership and influence skills—able to build trust, align cross-functional teams, and drive execution in a matrix environment. Excellent communication and presentation skills, including experience representing the organization at scientific meetings and external forums. Comprehensive understanding of compliance and regulatory frameworks governing scientific exchange and industry collaborations. Travel Travel approximately ~20–30%, including domestic and occasional international travel to scientific congresses, investigator meetings, advisory boards, field team visits, Medical Affairs planning sessions, and cross-functional onsite meetings. These positions are eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level. US Salary Range: $225,000 - $240,000 #LI-DNI