Supervisor – Isotope Production

At RayzeBio, every day is an opportunity to ignite meaningful change. As a wholly-owned subsidiary of Bristol Myers Squibb, RayzeBio blends the nimble, pioneering spirit of an emergent biotech with the global expertise and resources of a leading innovator in oncology. Our mission is to develop transformative radiopharmaceutical therapies that offer new hope for patients living with cancer. Here, you’ll join a multidisciplinary team where your ideas are valued, your expertise is amplified, and collaboration is at the heart of everything we do. From day one, expect to make an immediate impact—on our science, on our teams, and most importantly, on patients. Learn more about RayzeBio: https://careers.bms.com/rayzebio/ The Supervisor – Isotope Production, reporting to the Associate Director – Radiopharmaceuticals, plays a critical role in delivering RayzeBio’s innovative radiopharmaceutical products to patients. This position supports the implementation and routine execution of a novel isotope production program manufacturing clinical and commercial‑scale radioisotopes. The Supervisor – Isotope Production provides day‑to‑day operational leadership for isotope production activities and serves as a key point of contact on the production floor, coordinating and guiding a team of operators working under Good Manufacturing Practices (GMP). This role is also a frontline leader for radiation safety, compliance, and operational discipline within the manufacturing suites. Job Responsibilities Essential duties and responsibilities include the following. Other duties may be assigned. Provide day‑to‑day operational oversight of radioisotope production activities, including scheduling, material preparation, line clearance, equipment setup, and batch record execution, ensuring compliance with GMP, NRC regulations, and internal expectations. Serve as a functional lead for production operators by providing guidance, task coordination, and on‑the‑floor support to ensure safe, compliant, and efficient execution of manufacturing activities. Support onboarding and training efforts for production staff and promote adherence to GMP and radiation safety best practices during manufacturing activities. Support and execute validation activities associated with isotope production at the clinal and commercial scale. Collaborate with cross‑functional partners including Quality, Safety, Engineering, Development, and Management to identify opportunities for process optimization, troubleshooting, and continuous improvement. Assist Isotope Production Management with the compilation of operational KPIs and support the investigation and resolution of quality events (e.g., deviations, OOS, and nonconformances). Support inventory management activities, including consumables, spare parts, cleaning supplies, and personal protective equipment (PPE) Promote and reinforce a strong culture of safety, quality, and compliance with EHS and Radiation Safety programs. Author, review, and revise production technical documentation (e.g., SOPs, forms, batch records) as needed to support manufacturing operations. Education and Experience: Demonstrated experience leading work activities, mentoring peers, or serving in a lead or senior operational role within a manufacturing or laboratory environment; prior formal supervisory experience is beneficial but not required. 3–5 years of experience operating in a GMP‑regulated environment. Hands‑on experience working in hot cells and/or gloveboxes strongly preferred. Associate’s or Bachelor’s degree in a STEM field preferred, or equivalent combination of education and relevant experience.   Skills and Qualification: Fluency in English. Strong knowledge of GMP practice. Knowledge of radiation safety principles. Excellent professional ethics, integrity, and ability to maintain confidential information. Utilizes AI tools to enhance individual productivity and quality of work Well organized and detail oriented. Strong interpersonal communication skills. Motivated, adaptable, and able to work under pressure while meeting the needs of the production schedule. Physical Demands: While performing the duties of this job, the employee is regularly required to sit, reach with hands and arms, and talk or hear. The employee must occasionally lift and/or move up to 50 pounds. Specific vision abilities required by this job include close vision and distance vision. Must be willing to wear personal protective equipment (PPE) for long periods.   This is a position that requires working in a laboratory environment, protective clothing, gloves, and safety glasses are required while working in a laboratory environment with radioactive materials. Work Environment: The noise level in the work environment is usually moderate. If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Compensation Overview: Indianapolis - RayzeBio - IN: $96,148 - $116,508
 The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.  Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.   Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include: Health Coverage: Medical, pharmacy, dental, and vision care. Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP). Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support. ​Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day. All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown. *Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program. RayzeBio and Bristol Myers Squibb RayzeBio was acquired by Bristol Myers Squibb (BMS) in 2024 and is a wholly-owned subsidiary of BMS; however, RayzeBio will continue to operate as a standalone organization. Supporting People with Disabilities BMS and RayzeBio are dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement. Candidate Rights BMS and RayzeBio will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/ Data Protection We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection/ Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations. If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at TAEnablement@bms.com. Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response. R1599934 : Supervisor – Isotope Production